Conditional deletion of melanin-concentrating hormone receptor 1 from GABAergic neurons increases locomotor activity
Objective: Melanin-concentrating hormone (MCH) plays a key role in regulating energy balance. MCH acts via its receptor MCHR1, and MCHR1 deletion increases energy expenditure and locomotor activity, which is associated with a hyperdopaminergic state. Since MCHR1 expression is widespread, the neurons...
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Main Authors: | Melissa J. Chee (Author), Alex J. Hebert (Author), Nadege Briançon (Author), Stephen E. Flaherty, III (Author), Pavlos Pissios (Author), Eleftheria Maratos-Flier (Author) |
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Format: | Book |
Published: |
Elsevier,
2019-11-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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