Systemic Evaluation on the Pharmacokinetics of Platinum-Based Anticancer Drugs From Animal to Cell Level: Based on Total Platinum and Intact Drugs

• Main Authors: Zhiying Qin (Author), Guanghui Ren (Author), Jinjie Yuan (Author), Huili Chen (Author), Yang Lu (Author), Ning Li (Author), Yongjie Zhang (Author), Xijing Chen (Author), Di Zhao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cisplatin, carboplatin, and oxaliplatin are the common platinum-based anticancer drugs widely used in the chemotherapeutic treatment of solid tumors in clinic. However, the comprehensive pharmacokinetics of platinum-based anticancer drugs has not been fully understood yet. This leads to many limitat...