Design, synthesis, and evaluation of novel 2-substituted 1,4-benzenediol library as antimicrobial agents against clinically relevant pathogens

• Main Authors: Daiane Flores Dalla Lana (Author), Bruna Gerardon Batista (Author), Gabriella da Rosa Machado (Author), Mário Lettieri Teixeira (Author), Luís Flávio Souza de Oliveira (Author), Michel Mansur Machado (Author), Saulo Fernandes de Andrade (Author), William Lopes (Author), Marilene Henning Vainstein (Author), Alejandro Peixoto de Abreu Lima (Author), Enrique Pandolfi (Author), Edilma Elayne Silva (Author), Alexandre Meneghello Fuentefria (Author), Gustavo Pozza Silveira (Author)
• Format: Book
• Published: Elsevier, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Development of new antimicrobial agents, capable of combating resistant and multidrug-resistant fungal and bacterial clinical strains, is necessary. This study presents the synthesis and antimicrobial screening of 42 2-substituted-1,4-benzenediols, being 10 novel compounds. In total, 23 compounds sh...