Targeting L-type amino acid transporter 1 in urological malignancy: Current status and future perspective

• Main Authors: Sangjon Pae (Author), Shinichi Sakamoto (Author), Xue Zhao (Author), Shinpei Saito (Author), Takaaki Tamura (Author), Yusuke Imamura (Author), Tomokazu Sazuka (Author), Yoshie Reien (Author), Yuri Hirayama (Author), Hirofumi Hashimoto (Author), Yoshikatsu Kanai (Author), Tomohiko Ichikawa (Author), Naohiko Anzai (Author)
• Format: Book
• Published: Elsevier, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Amino acid transporters are responsible for the uptake of amino acids, critical for cell proliferation. L-type amino acid transporters play a major role in the uptake of essential amino acids. L-type amino acid transporter 1 (LAT1) exerts its functional properties by forming a dimer with 4F2hc. Util...