New Topics in Vasopressin Receptors and Approach to Novel Drugs: Effects of Vasopressin Receptor on Regulations of Hormone Secretion and Metabolisms of Glucose, Fat, and Protein

The neurohypophyseal peptide [Arg8]-vasopressin (AVP) is involved in diverse functions such as the regulation of body fluid homeostasis, metabolism, and hormone secretion. In this study, we analyzed the functional roles of AVP in hormone release and metabolisms of glucose, fat, and protein in mutant...

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Main Author: Akito Tanoue (Author)
Format: Book
Published: Elsevier, 2009-01-01T00:00:00Z.
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100 1 0 |a Akito Tanoue  |e author 
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500 |a 10.1254/jphs.08R15FM 
520 |a The neurohypophyseal peptide [Arg8]-vasopressin (AVP) is involved in diverse functions such as the regulation of body fluid homeostasis, metabolism, and hormone secretion. In this study, we analyzed the functional roles of AVP in hormone release and metabolisms of glucose, fat, and protein in mutant mice lacking the V1a (V1aR-KO) or V1b receptor (V1bR-KO). Our study suggests that antagonists for the receptors could affect the hormone secretions and metabolisms. Keywords:: arginine vasopressin, metabolism, hormone, adrenocorticotropic hormone (ACTH) 
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690 |a Therapeutics. Pharmacology 
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786 0 |n Journal of Pharmacological Sciences, Vol 109, Iss 1, Pp 50-52 (2009) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S1347861319312976 
787 0 |n https://doaj.org/toc/1347-8613 
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