Doxorubicin Changes Bax /Bcl-xL Ratio, Caspase-8 and 9 in Breast Cancer Cells

• मुख्य लेखकों: Simin Sharifi (लेखक), Jaleh Barar (लेखक), Mohammad Saeid Hejazi (लेखक), Nasser Samadi (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Tabriz University of Medical Sciences, 2015-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Purpose: Doxorubicin is administrated as a single agent in first-line therapy of breast cancer to induce apoptosis in tumor cells. Bax, Bcl-xL, Caspase-8 and 9 proteins are involved in induction of apoptosis. The present study describes Bax, Bcl-xL gene expression and Caspase-8 and 9 protein levels...