Doxorubicin Changes Bax /Bcl-xL Ratio, Caspase-8 and 9 in Breast Cancer Cells

• Príomhchruthaitheoirí: Simin Sharifi (Údar), Jaleh Barar (Údar), Mohammad Saeid Hejazi (Údar), Nasser Samadi (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Tabriz University of Medical Sciences, 2015-09-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Purpose: Doxorubicin is administrated as a single agent in first-line therapy of breast cancer to induce apoptosis in tumor cells. Bax, Bcl-xL, Caspase-8 and 9 proteins are involved in induction of apoptosis. The present study describes Bax, Bcl-xL gene expression and Caspase-8 and 9 protein levels...