Doxorubicin Changes Bax /Bcl-xL Ratio, Caspase-8 and 9 in Breast Cancer Cells

Purpose: Doxorubicin is administrated as a single agent in first-line therapy of breast cancer to induce apoptosis in tumor cells. Bax, Bcl-xL, Caspase-8 and 9 proteins are involved in induction of apoptosis. The present study describes Bax, Bcl-xL gene expression and Caspase-8 and 9 protein levels...

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Main Authors: Simin Sharifi (Author), Jaleh Barar (Author), Mohammad Saeid Hejazi (Author), Nasser Samadi (Author)
Format: Book
Published: Tabriz University of Medical Sciences, 2015-09-01T00:00:00Z.
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3rd Floor Main Library

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