Sodium or Not Sodium: Should Its Presence Affect the Accuracy of Pose Prediction in Docking GPCR Antagonists?

The function of the allosteric sodium ion in stabilizing the inactive form of GPCRs has been extensively described in the past decades. Its presence has been reported to be essential for the binding of antagonist molecules in the orthosteric site of these very important therapeutical targets. Among...

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Main Authors: Davide Bassani (Author), Matteo Pavan (Author), Mattia Sturlese (Author), Stefano Moro (Author)
Format: Book
Published: MDPI AG, 2022-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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