Low concentrations of clarithromycin upregulate cellular antioxidant enzymes and phosphorylation of extracellular signal-regulated kinase in human small airway epithelial cells

• Päätekijät: Kuninori Iwayama (Tekijä), Junpei Kimura (Tekijä), Aya Mishima (Tekijä), Ayuko Kusakabe (Tekijä), Ko-ichi Ohtaki (Tekijä), Yoshiko Tampo (Tekijä), Nobumasa Hayase (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: BMC, 2018-09-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Background It is well known that low-dose, long-term macrolide therapy is effective against chronic inflammatory airway diseases. Oxidative stress is considered to be a key pathogenesis factor in those diseases. However, the mechanism of action of low-dose, long-term macrolide therapy remai...