Dual Targeting EGFR and STAT3 With Erlotinib and Alantolactone Co-Loaded PLGA Nanoparticles for Pancreatic Cancer Treatment

• Main Authors: Shihui Bao (Author), Hailun Zheng (Author), Jinyao Ye (Author), Huirong Huang (Author), Bin Zhou (Author), Qing Yao (Author), Guangyong Lin (Author), Hailin Zhang (Author), Longfa Kou (Author), Ruijie Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pancreatic cancer (PC) is one of the most common malignancies and also a leading cause of cancer-related mortality worldwide. Many studies have shown that epidermal growth factor receptor (EGFR) is highly expressed in PC, which provides a potential target for PC treatment. However, EGFR inhibitors u...