5-Lipoxygenase-Dependent Recruitment of Neutrophils and Macrophages by Eotaxin-Stimulated Murine Eosinophils

• Main Authors: Ricardo Alves Luz (Author), Pedro Xavier-Elsas (Author), Bianca de Luca (Author), Daniela Masid- (Author), Priscila Soares Cauduro (Author), Luiz Carlos Gondar Arcanjo (Author), Ana Carolina Cordeiro Faria dos Santos (Author), Ivi Cristina Maria de Oliveira (Author), Maria Ignez Capella Gaspar-Elsas (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The roles of eosinophils in antimicrobial defense remain incompletely understood. In ovalbumin-sensitized mice, eosinophils are selectively recruited to the peritoneal cavity by antigen, eotaxin, or leukotriene(LT)B4, a 5-lipoxygenase (5-LO) metabolite. 5-LO blockade prevents responses to both antig...