The Designed Pore-Forming Antimicrobial Peptide C14R Combines Excellent Activity against the Major Opportunistic Human Pathogen <i>Pseudomonas aeruginosa</i> with Low Cytotoxicity

• প্রধান লেখক: Vanessa Mildenberger (লেখক), Daniel Alpízar-Pedraza (লেখক), Ernesto M. Martell-Huguet (লেখক), Markus Krämer (লেখক), Grigory Bolotnikov (লেখক), Anselmo J. Otero-Gonzalez (লেখক), Tanja Weil (লেখক), Armando Rodriguez-Alfonso (লেখক), Nico Preising (লেখক), Ludger Ständker (লেখক), Verena Vogel (লেখক), Barbara Spellerberg (লেখক), Ann-Kathrin Kissmann (লেখক), Frank Rosenau (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2024-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The diminishing portfolio of mankind's available antibiotics urges science to develop novel potent drugs. Here, we present a peptide fitting the typical blueprint of amphipathic and membrane-active antimicrobial peptides, denominated C14R. This 2 kDa peptide consists of 16 amino acid residues,...