Novel sulphonamides incorporating triazene moieties show powerful carbonic anhydrase I and II inhibitory properties

• Main Authors: Sinan Bilginer (Author), Baris Gonder (Author), Halise Inci Gul (Author), Ruya Kaya (Author), Ilhami Gulcin (Author), Baris Anil (Author), Claudiu T. Supuran (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A series of compounds incorporating 3-(3-(2/3/4-substituted phenyl)triaz-1-en-1-yl) benzenesulfonamide moieties were synthesised and their chemical structure was confirmed by physico-chemical methods. Carbonic anhydrase (CA, EC 4.2.1.1) inhibitory effects of the compounds were evaluated against huma...