DELAYED URIC ACID ACCUMULATION IN PLASMA PROVIDES ADDITIONAL ANTI- OXIDANT PROTECTION AGAINST IRON- TRIGGERED OXIDATIVE STRESS AFTER A WINGATE TEST

• Main Authors: TP Souza-Junior (Author), L Lorenço-Lima (Author), D Ganini (Author), CV Vardaris (Author), TG Polotow (Author), MP Barros (Author)
• Format: Book
• Published: Termedia Publishing House, 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Reactive oxygen species are produced during anaerobic exercise mostly by Fe ions released into plasma and endothelial/muscle xanthine oxidase activation that generates uric acid (UA) as the endpoint metabolite. Paradoxically, UA is considered a major antioxidant by virtue of being able to chelate pr...