Two Endogenous Antiangiogenic Inhibitors, Endostatin and Angiostatin, Demonstrate Biphasic Curves in their Antitumor Profiles
Angiogenesis refers to growth of blood vessels from pre-existing ones. In 1971, Folkman proposed that by choking off the blood supply to tumors, they are starved, leading to their demise. A few years ago, the monoclonal antibody Avastin became the first antiangiogenic biological approved by FDA, for...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
SAGE Publishing,
2011-07-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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