Development and validation of liquid chromatography-tandem mass spectrometry method to quantify dasatinib in plasma and its application to a pharmacokinetic study
Abstract Dasatinib, a potent oral multi-targeted kinase inhibitor against Src and Bcr-Abl, can decrease inflammatory response in sepsis. A simple and cost-effective method for determination of an effective dose dasatinib was established. This method was validated in human plasma, with the aim of red...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
Universidade de São Paulo,
2023-05-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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