A Rare Case of Osteomyelitis of an Ankle Caused by <i>Mycobacterium chelonae</i>
<i>Mycobacterium chelonae</i>, a rapidly growing nontuberculous mycobacterium, is usually described as a causative agent of soft tissue infections (postsurgical, posttraumatic, posttransplantation, postinjection, catheter infection, etc.), but only rarely as a cause of osteomyelitis. The...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
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MDPI AG,
2023-01-01T00:00:00Z.
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| Summary: | <i>Mycobacterium chelonae</i>, a rapidly growing nontuberculous mycobacterium, is usually described as a causative agent of soft tissue infections (postsurgical, posttraumatic, posttransplantation, postinjection, catheter infection, etc.), but only rarely as a cause of osteomyelitis. The authors describe a case report of a 72-year-old man with osteomyelitis of the talus. Initially, the infection was assessed as a soft tissue infection, without any osteolytic changes on the X-ray. After cultivation with subsequent targeted molecular typing of the <i>rpo</i>B gene, <i>M. chelonae</i> was identified from the affected tissue. The bone involvement was subsequently detected on MRI and confirmed histologically with findings of the granulomatous tissue and acid-fast bacilli. The patient was initially treated intravenously with a combination of tigecycline, amikacin, and moxifloxacin for 4 weeks, after which the oral combination of doxycycline and moxifloxacin continued. Identification of the infecting pathogen using molecular typing thus helped to establish the correct diagnosis and represents a rarely described case of osteomyelitis caused by <i>M. chelonae.</i> |
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| Item Description: | 10.3390/antibiotics12010097 2079-6382 |