Rapid and specific chromatography method on monolithic RP-column for determination of high-dose methotrexate pharmacokinetics in sera of cancer patients admitted to Shiraz Amir Hospital
Introduction: methotrexate (MTX) is a routinely used antifolate for the treatment of solid tumors and hematologic malignancies. However, high-dose MTX can lead to severe side effects and the patients are required to receive leucovorin rescue. Hence, we aimed to develop a fast and specific HPLC metho...
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| Main Authors: | , , , , , |
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| Format: | Book |
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Shiraz University of Medical Sciences,
2020-09-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |