In Vitro and In Vivo Effect of pH-Sensitive PLGA-TPGS-Based Hybrid Nanoparticles Loaded with Doxorubicin for Breast Cancer Therapy

• Autori principali: Renata S. Fernandes (Autore), Raquel Gregório Arribada (Autore), Juliana O. Silva (Autore), Armando Silva-Cunha (Autore), Danyelle M. Townsend (Autore), Lucas A. M. Ferreira (Autore), André L. B. Barros (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2022-11-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Doxorubicin (DOX) is an antineoplastic agent clinically employed for treating breast cancer patients. Despite its effectiveness, its inherent adverse toxic side effects often limit its clinical application. To overcome these drawbacks, lipid-polymer hybrid nanoparticles (LPNP) arise as promising nan...