Inhibition of the RIP3/MLKL/TRPM7 necroptotic pathway ameliorates diabetes mellitus-induced erectile dysfunction by reducing cell death, fibrosis, and inflammation

• Auteurs principaux: Lipan Niu (Auteur), Pei Yang (Auteur), Bingbing Zhu (Auteur), Xiufang Jin (Auteur), Chengxia Yang (Auteur), Xijia Zhang (Auteur), Yulian Liu (Auteur), Rui Zhang (Auteur), Fengxia Liu (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Diabetes mellitus-induced erectile dysfunction (DMED) is a common complication in patients with diabetes mellitus. Necroptosis is regarded as a form of cell death that is intimately associated with the inflammatory response, which is not only initiated by inflammatory factors such as TNF-α, but also...