Inhibition of the RIP3/MLKL/TRPM7 necroptotic pathway ameliorates diabetes mellitus-induced erectile dysfunction by reducing cell death, fibrosis, and inflammation

• Main Authors: Lipan Niu (Author), Pei Yang (Author), Bingbing Zhu (Author), Xiufang Jin (Author), Chengxia Yang (Author), Xijia Zhang (Author), Yulian Liu (Author), Rui Zhang (Author), Fengxia Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetes mellitus-induced erectile dysfunction (DMED) is a common complication in patients with diabetes mellitus. Necroptosis is regarded as a form of cell death that is intimately associated with the inflammatory response, which is not only initiated by inflammatory factors such as TNF-α, but also...