Population Pharmacokinetic-Pharmacodynamic Analysis of a Reserpine-Induced Myalgia Model in Rats

• Main Authors: Gloria M. Alfosea-Cuadrado (Author), Javier Zarzoso-Foj (Author), Albert Adell (Author), Alfonso A. Valverde-Navarro (Author), Eva M. González-Soler (Author), Víctor Mangas-Sanjuán (Author), Arantxa Blasco-Serra (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

(1) Background: Fibromyalgia syndrome (FMS) is a chronic pain condition with widespread pain and multiple comorbidities, for which conventional therapies offer limited benefits. The reserpine-induced myalgia (RIM) model is an efficient animal model of FMS in rodents. This study aimed to develop a ph...