Reprogramming of Adult Retinal Müller Glial Cells into Human-Induced Pluripotent Stem Cells as an Efficient Source of Retinal Cells

• Main Authors: Amélie Slembrouck-Brec (Author), Amélie Rodrigues (Author), Oriane Rabesandratana (Author), Giuliana Gagliardi (Author), Céline Nanteau (Author), Stéphane Fouquet (Author), Gilles Thuret (Author), Sacha Reichman (Author), Gael Orieux (Author), Olivier Goureau (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The reprogramming of human somatic cells to induced pluripotent stem cells (iPSCs) has broad applications in regenerative medicine. The generation of self-organized retinal structures from these iPSCs offers the opportunity to study retinal development and model-specific retinal disease with patient...