High Expression of Sphingosine Kinase 1 in Estrogen and Progesterone Receptors-Negative Breast Cancer

• Main Authors: Azadeh Sadat Nazouri (Author), omolbanin asadpour (Author), Shahriar Dabiri (Author), Bahram Pourseyedi (Author), Mohamad reza Lashkarizadeh (Author), Hamid Zeinalyneghad (Author)
• Format: Book
• Published: Iranian Society of Pathology, 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background & objective: Breast cancer is the leading cause of cancer related death in females. Sphingosine kinase 1 (SPHK1) and its product sphingosine-1-phosphate (S1P) are the essential key regulator molecules in breast cancer through their ability to promote cell proliferation, angiogenesis,...