Amyotrophic Lateral Sclerosis, a Multisystem Pathology: Insights into the Role of TNFα

• Main Authors: Massimo Tortarolo (Author), Daniele Lo Coco (Author), Pietro Veglianese (Author), Antonio Vallarola (Author), Maria Teresa Giordana (Author), Gabriella Marcon (Author), Ettore Beghi (Author), Marco Poloni (Author), Michael J. Strong (Author), Anand M. Iyer (Author), Eleonora Aronica (Author), Caterina Bendotti (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Amyotrophic lateral sclerosis (ALS) is considered a multifactorial, multisystem disease in which inflammation and the immune system play important roles in development and progression. The pleiotropic cytokine TNFα is one of the major players governing the inflammation in the central nervous system...