MicroRNA-466 and microRNA-200 increase endothelial permeability in hyperglycemia by targeting Claudin-5

• Main Authors: Marisa Kujawa (Author), Megan O'Meara (Author), Hainan Li (Author), Liping Xu (Author), Sai Pranathi Meda Venkata (Author), Huong Nguyen (Author), Morgan Minjares (Author), Kezhong Zhang (Author), Jie-Mei Wang (Author)
• Format: Book
• Published: Elsevier, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Endothelial cell (EC) permeability is essential to vascular homeostasis in diabetes. MicroRNAs are critical gene regulators whose roles in the EC permeability have yet to be characterized. This study aims to examine the change in cell permeability induced by miR-200 and miR-466 in ECs. Human aortic...