Error-corrected sequencing strategies enable comprehensive detection of leukemic mutations relevant for diagnosis and minimal residual disease monitoring

• Үндсэн зохиолчид: Erin L. Crowgey (Зохиогч), Nitin Mahajan (Зохиогч), Wing Hing Wong (Зохиогч), Anilkumar Gopalakrishnapillai (Зохиогч), Sonali P. Barwe (Зохиогч), E. Anders Kolb (Зохиогч), Todd E. Druley (Зохиогч)
• Формат: Ном
• Хэвлэсэн: BMC, 2020-03-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Abstract Background Pediatric leukemias have a diverse genomic landscape associated with complex structural variants, including gene fusions, insertions and deletions, and single nucleotide variants. Routine karyotype and fluorescence in situ hybridization (FISH) techniques lack sensitivity for smal...