Effects of a new antiarrhythmic drug SS-68 on electrical activity in working atrial and ventricular myocardium of mouse and their ionic mechanisms

• Ngā kaituhi matua: Saida K. Bogus (Author), Denis V. Abramochkin (Author), Pavel A. Galenko-Yaroshevsky (Author), Konstantin F. Suzdalev (Author)
• Hōputu: Pukapuka
• I whakaputaina: Elsevier, 2015-08-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

SS-68 is a derivative of indole, which demonstrated strong antiarrhythmic effects not associated with significant QT prolongation in dog models of atrial fibrillation. Therefore, SS-68 was proposed as a new antiarrhythmic drug and the present study is the first describing its effects on action poten...