Fibroblasts and endothelial cells interplay drives hypertrophic scar formation: Insights from in vitro and in vivo models

• Main Authors: Yaxin Tan (Author), Mengde Zhang (Author), Yi Kong (Author), Fanliang Zhang (Author), Yuzhen Wang (Author), Yuyan Huang (Author), Wei Song (Author), Zhao Li (Author), Linhao Hou (Author), Liting Liang (Author), Xu Guo (Author), Qinghua Liu (Author), Yu Feng (Author), Chao Zhang (Author), Xiaobing Fu (Author), Sha Huang (Author)
• Format: Book
• Published: Wiley, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Hypertrophic scar formation is influenced by the intricate interplay between fibroblasts and endothelial cells. In this study, we investigated this relationship using in vitro and in vivo models. Clinical observations revealed distinct morphological changes and increased vascularity at path...