Activation of the Nrf2/Keap1 signaling pathway mediates the neuroprotective effect of Perillyl alcohol against cerebral hypoxic-ischemic damage in neonatal rats

• Main Authors: Yu Fang (Author), Yihui Zheng (Author), Qiqi Gao (Author), Mengdan Pang (Author), Yiqing Wu (Author), Xiaoli Feng (Author), Xiaoyue Tao (Author), Yingying Hu (Author), Zhenlang Lin (Author), Wei Lin (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neonatal hypoxic-ischemic encephalopathy (HIE) is a severe disease with a poor prognosis, whose clinical treatment is still limited to therapeutic hypothermia with limited efficacy. Perillyl alcohol (POH), a natural monoterpene found in various plant essential oils, has shown neuroprotective propert...