Ethosomal gel for rectal transmucosal delivery of domperidone: design of experiment, in vitro, and in vivo evaluation

• Main Authors: Wedad Sakran (Author), Rania S. Abdel-Rashid (Author), Fatma Saleh (Author), Raghda Abdel-Monem (Author)
• 格式: 圖書
• 出版: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Despite high efficiency of domperidone (DOM) in prophylaxis of emesis accompanied with radiotherapy and chemotherapy, it still can bother cancer patients by its powerful side effects and difficulty of its oral administration. The study was designed to develop and optimize DOM loaded ethosomal gel fo...