Self-assembled FGF21 nanoparticles alleviate drug-induced acute liver injury

• Autori principali: Zhiwei Huang (Autore), Hengcai Wang (Autore), Changju Chun (Autore), Xinze Li (Autore), Shihao Xu (Autore), Yingzheng Zhao (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Acetaminophen (N-acetyl-p-aminophenol, APAP) is a common antipyretic agent and analgesic. An overdose of APAP can result in acute liver injury (ALI). Oxidative stress and inflammation are central to liver injury. N-acetylcysteine (NAC), a precursor of glutathione, is used commonly in clinical settin...