Edaravone Plays Protective Effects on LPS-Induced Microglia by Switching M1/M2 Phenotypes and Regulating NLRP3 Inflammasome Activation

• Hlavní autoři: Jiping Li (Autor), Xinping Dai (Autor), Liuyi zhou (Autor), Xinxiu Li (Autor), Dongxiao Pan (Autor)
• Médium: Kniha
• Vydáno: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Parkinson's disease is a neurodegenerative disorder in which activated microglia may appear prior to motor symptoms, but the specific therapeutic mechanisms remain unclear. This study investigated the potential effects of Edaravone (EDA) on M1/M2 polarization of microglia in rats with dopaminer...