A Photoactive Supramolecular Complex Targeting PD-L1 Reveals a Weak Correlation between Photoactivation Efficiency and Receptor Expression Levels in Non-Small-Cell Lung Cancer Tumor Models

• Main Authors: Pietro Delcanale (Author), Manuela Maria Alampi (Author), Andrea Mussini (Author), Claudia Fumarola (Author), Maricla Galetti (Author), Pier Giorgio Petronini (Author), Cristiano Viappiani (Author), Stefano Bruno (Author), Stefania Abbruzzetti (Author)
• Format: Book
• Published: MDPI AG, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Photo-immunotherapy uses antibodies conjugated to photosensitizers to produce nanostructured constructs endowed with targeting properties and photo-inactivation capabilities towards tumor cells. The superficial receptor density on cancer cells is considered a determining factor for the efficacy of t...