F7 and topotecan co-loaded thermosensitive liposome as a nano-drug delivery system for tumor hyperthermia

• Main Authors: Chunyang Du (Author), Shuangshuang Li (Author), Yuan Li (Author), Hervé Galons (Author), Na Guo (Author), Yuou Teng (Author), Yongmin Zhang (Author), Mingyuan Li (Author), Peng Yu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In order to enhance the targeting efficiency and reduce anti-tumor drug's side effects, topotecan (TPT) and F7 were co-loaded in thermosensitive liposomes (F7-TPT-TSL), which show enhanced permeability and retention in tumors, as well as local controlled release by heating in vitro. TPT is a wa...