Fluoxetine increases astrocytic glucose uptake and glycolysis in corticosterone-induced depression through restricting GR-TXNIP-GLUT1 Pathway

• Auteurs principaux: Shu-Man Pan (Auteur), Yi-Fan Zhou (Auteur), Na Zuo (Auteur), Rui-Qing Jiao (Auteur), Ling-Dong Kong (Auteur), Ying Pan (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Antidepressant fluoxetine can affect cerebral glucose metabolism in clinic, but the underlying molecular mechanism remains poorly understood. Here, we examined the effect of fluoxetine on brain regional glucose metabolism in a rat model of depression induced by repeated corticosterone injection, and...