Delivery of N-heterocyclic drugs, acids, phenols, and thiols via Tailor−made Self−immolative linkers

Delivery of N-heterocyclic drugs, acids, phenols, and thiols via Tailor−made Self−immolative linkers

Heterocyclic drugs display diverse pharmacological activities and metabolic stability. However, their poor solubility and pharmacokinetic properties often compromise bioavailability and clinical outcomes. Nevertheless, the prodrug approach provides a viable strategy to overcome unwanted attributes o...

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Main Authors: Vahid Barati (Author), Anna Hruzíková (Author), Eliška Procházková (Author), Martin Zavřel (Author), Jaroslav Kozák (Author), Jana Trylčová (Author), Dominik Rejman (Author), Jan Weber (Author), Kateřina Bogdanová (Author), Milan Kolář (Author), Ondřej Baszczyňski (Author)
Format: Book
Published: Elsevier, 2024-12-01T00:00:00Z.
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