A Method for Evaluating Robustness of Limited Sampling Strategies-Exemplified by Serum Iohexol Clearance for Determination of Measured Glomerular Filtration Rate

• 主要な著者: Markus Hovd (著者), Ida Robertsen (著者), Jean-Baptiste Woillard (著者), Anders Åsberg (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2023-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

In combination with Bayesian estimates based on a population pharmacokinetic model, limited sampling strategies (LSS) may reduce the number of samples required for individual pharmacokinetic parameter estimations. Such strategies reduce the burden when assessing the area under the concentration vers...