Single immunization with an influenza hemagglutinin nanoparticle‐based vaccine elicits durable protective immunity

• Main Authors: Shiho Chiba (Author), Tadashi Maemura (Author), Kathryn Loeffler (Author), Steven J. Frey (Author), Chunyang Gu (Author), Asim Biswas (Author), Masato Hatta (Author), Yoshihiro Kawaoka (Author), Ravi S. Kane (Author)
• Format: Book
• Published: Wiley, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Vaccination is the most effective strategy to combat influenza. Ideally, potent and persistent vaccine effects would be induced with a single vaccine dose. Here, we designed a virus‐like particle (VLP)‐based vaccine presenting multiple copies of the influenza hemagglutinin (HA) from A/Puert...