Novel variants in TUBB8 gene cause multiple phenotypic abnormalities in human oocytes and early embryos

• Main Authors: Tingwenyi Hu (Author), Chong Li (Author), Sen Qiao (Author), Weiwei Liu (Author), Wei Han (Author), Wei Li (Author), Rong Shi (Author), Xia Xue (Author), Juanzi Shi (Author), Guoning Huang (Author), Tingting Lin (Author)
• Format: Book
• Published: BMC, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The genotype-phenotype relationships between TUBB8 variants and female infertility are difficult to clearly define due to the complex inheritance patterns and the highly heterogeneous phenotypes. This study aims to identify novel TUBB8 variants and relevant phenotypes in more inf...