The Chronic Effect of Endurance Training On Jip3 Gene Expression in Soleus Muscle of Male Wistar Rats
Background & Objective: Adaptations in neuromuscular system are due to changes in the expression and activity of proteins and its transmitters. JIP 3 protein plays a role in the regulation of structure and function of neurons as well as the establishment of multi-nuclear muscle cells. Considerin...
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| Main Authors: | , , |
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| Format: | Book |
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Fasa University of Medical Sciences,
2016-11-01T00:00:00Z.
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| Summary: | Background & Objective: Adaptations in neuromuscular system are due to changes in the expression and activity of proteins and its transmitters. JIP 3 protein plays a role in the regulation of structure and function of neurons as well as the establishment of multi-nuclear muscle cells. Considering the effects of exercise on neuromuscular system, the present study aimed to investigate the effects of 6 weeks of endurance training on JIP3 gene expression in soleus muscle of male Wistar rats. Material & Methods: Ten Wistar male rats were randomly assigned in two groups: trained and control. Endurance training protocol was performed for 6 weeks. Forty eight hours after final training session, the rats were dissected, and soleus muscle was removed. JIP3 gene expression was performed through Real Time PCR method. Results: Endurance training increased JIP3 gene expression significantly compared to the control group. Conclusion: It appears that a period of endurance training increases intramuscular gene expression of JIP3 through this can lead to a better consistency and functionality in the muscles. |
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| Item Description: | 2228-5105 2783-1523 |