SARS-CoV-2 evolution in a patient with secondary B-cell immunodeficiency: A clinical case

• Main Authors: Olgo A. Mukhina (Author), Daria S. Fomina (Author), Vasiliy V. Parshin (Author), Vladimir A. Gushchin (Author), Inna V. Dolzhikova (Author), Alexey M. Shchetinin (Author), Dmitriy M. Chudakov (Author), Evgeniia Alekseeva (Author), Dmitriy Korostin (Author), Georgii A. Bazykin (Author), Galya Klink (Author), Denis Yu. Logunov (Author), Maryana A. Lysenko (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The article highlights the course of long-term SARS-CoV-2 infection in a patient with a secondary immunodeficiency developed with B-cell-depleting therapy of the underlying disease. Analysis of the intrapatient virus evolution revealed an inpatient S:G75A mutation that alters the 72GTNGTKR78 motif o...