Expression patterns and prognostic significances of RRM1 and ERCC1 in pancreatic carcinoma and cholangiocarcinoma

• Main Authors: Khushbu Khetan (Author), Ranjit K Sahoo (Author), Vandana Baloda (Author), Shalimar (Author), Sreenivas Vishnubhatla (Author), Anoop Saraya (Author), Nihar Ranjan Dash (Author), Atul Sharma (Author), Siddhartha DattaGupta (Author), Prasenjit Das (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Aggressive pancreatobiliary tumors often require oxaliplatin-based therapies, instead of standard gemcitabine-based therapy and biomarker studies at diagnosis to decide the appropriate therapeutic regimen. The ribonucleotide Reductase catalytic subunit M1 (RRM1) and excision repair cross...