Formulation and characterization of lipid-based drug delivery system of raloxifene-microemulsion and self-microemulsifying drug delivery system

• Main Authors: Hetal Thakkar (Author), Jitesh Nangesh (Author), Mayur Parmar (Author), Divyakant Patel (Author)
• פורמט: ספר
• יצא לאור: Wolters Kluwer Medknow Publications, 2011-01-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Background : Raloxifene, a second-generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women is administered orally in the form of a tablet. The absolute bioavailability of the drug is only 2% because of extensive hepatic first-pass metabolism. Lipid...