Combretastatin A-4 based thiophene derivatives as antitumor agent: Development of structure activity correlation model using 3D-QSAR, pharmacophore and docking studies

• Main Authors: Vijay K. Patel (Author), Avineesh Singh (Author), Deepak K. Jain (Author), Preeti Patel (Author), Ravichandran Veerasamy (Author), Prabodh C. Sharma (Author), Harish Rajak (Author)
• Format: Book
• Published: SpringerOpen, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The structure and ligand based synergistic approach is being applied to design ligands more correctly. The present report discloses the combination of structure and ligand based tactics i.e., molecular docking, energetic based pharmacophore, pharmacophore and atom based 3D-QSAR modeling for the anal...