Mice with missense and nonsense NF1 mutations display divergent phenotypes compared with human neurofibromatosis type I

Neurofibromatosis type 1 (NF1) is a common genetic disorder characterized by the occurrence of nerve sheath tumors and considerable clinical heterogeneity. Some translational studies have been limited by the lack of animal models available for assessing patient-specific mutations. In order to test t...

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Principais autores: Kairong Li (Autor), Ashley N. Turner (Autor), Min Chen (Autor), Stephanie N. Brosius (Autor), Trenton R. Schoeb (Autor), Ludwine M. Messiaen (Autor), David M. Bedwell (Autor), Kurt R. Zinn (Autor), Corina Anastasaki (Autor), David H. Gutmann (Autor), Bruce R. Korf (Autor), Robert A. Kesterson (Autor)
Formato: Livro
Publicado em: The Company of Biologists, 2016-07-01T00:00:00Z.
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