Pedunculoside alleviates cognitive deficits and neuronal cell apoptosis by activating the AMPK signaling cascade

• Autores principales: Liwei Li (Autor), Jinfeng Sun (Autor), Fan Chen (Autor), Li Xiong (Autor), Lingyu She (Autor), Tang Hao (Autor), Yuqing Zeng (Autor), Luyao Li (Autor), Wei Wang (Autor), Xia Zhao (Autor), Guang Liang (Autor)
• Formato: Libro
• Publicado: BMC, 2024-11-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Background Mitochondrial dysfunction emerges as an early pathological hallmark of Alzheimer's disease (AD). The reduction in mitochondrial membrane potential and the elevation of reactive oxygen species (ROS) production are pivotal in the initiation of neuronal cell apoptosis. Peduncul...