Use of a commercial agarose gel for analysis of urinary glycosaminoglycans in mucopolysaccharidoses

• Principais autores: Ana Carolina Breier (Autor), Jaqueline Cé (Autor), Janice Carneiro Coelho (Autor)
• Formato: Livro
• Publicado em: Universidade de São Paulo.
• Assuntos: article
• Acesso em linha: Connect to this object online.

ABSTRACT Mucopolysaccharidoses (MPS) are a group of inherited metabolic disorders caused by deficiency of enzymes that degrade glycosaminoglycans (GAGs). Urinary excretion of GAGs is a common feature of MPS, and is considered their major biomarker. We aimed to adapt the GAG electrophoresis method to...