Interleukin-1 as a Common Denominator from Autoinflammatory to Autoimmune Disorders: Premises, Perils, and Perspectives

• Main Authors: Giuseppe Lopalco (Author), Luca Cantarini (Author), Antonio Vitale (Author), Florenzo Iannone (Author), Maria Grazia Anelli (Author), Laura Andreozzi (Author), Giovanni Lapadula (Author), Mauro Galeazzi (Author), Donato Rigante (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A complex web of dynamic relationships between innate and adaptive immunity is now evident for many autoinflammatory and autoimmune disorders, the first deriving from abnormal activation of innate immune system without any conventional danger triggers and the latter from self-/non-self-discriminatio...