Systematic Comparison of Hospital-Wide Standard and Model-Based Therapeutic Drug Monitoring of Vancomycin in Adults

• Main Authors: Heleen Gastmans (Author), Erwin Dreesen (Author), Sebastian G. Wicha (Author), Nada Dia (Author), Ellen Spreuwers (Author), Annabel Dompas (Author), Karel Allegaert (Author), Stefanie Desmet (Author), Katrien Lagrou (Author), Willy E. Peetermans (Author), Yves Debaveye (Author), Isabel Spriet (Author), Matthias Gijsen (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We aimed to evaluate the predictive performance and predicted doses of a single-model approach or several multi-model approaches compared with the standard therapeutic drug monitoring (TDM)-based vancomycin dosing. We performed a hospital-wide monocentric retrospective study in adult patients treate...