Influence of genetic polymorphisms of multidrug and toxin extrusion protein 1 on its mRNA expression in peripheral blood cells

• Main Authors: Hitoshi Ando (Author), Kazuhiko Nakano (Author), Kentaro Ushijima (Author), Shinsuke Kurokawa (Author), Satoshi Washino (Author), Keiko Hosohata (Author), Tatsuo Morita (Author), Akio Fujimura (Author)
• Format: Book
• Published: Elsevier, 2016-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aimed to determine the effect of multidrug and toxin extrusion protein 1 (MATE1) genetic variants on its transcript expression in peripheral blood cells. Consistent with previous in vitro findings, MATE1 mRNA levels were significantly higher in subjects carrying rs2453579, but not rs22522...