Cutaneous nociceptors lack sensitisation, but reveal μ-opioid receptor-mediated reduction in excitability to mechanical stimulation in neuropathy

• Главные авторы: Schmidt Yvonne (Автор), Labuz Dominika (Автор), Heppenstall Paul A (Автор), Machelska Halina (Автор)
• Формат: ‌
• Опубликовано: SAGE Publishing, 2012-11-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Peripheral nerve injuries often trigger a hypersensitivity to tactile stimulation. Behavioural studies demonstrated efficient and side effect-free analgesia mediated by opioid receptors on peripheral sensory neurons. However, mechani...